Ephedra

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A systematic review of 117 studies found that ephedra and ephedrine promoted modest shortter weight loss (approximately 0.9 kg/month more than with placebo) but increased the risk of psychiatric, autonomic, gastrointestinal, and cardiac complications by a factor of 2.2 to 3.6.[1].

An analysis of adverse reactions reported to poison control centers found that products containing ephedra accounted for 64% of all adverse reactions to herbs in the United States, yet these products represented only 0.82% of herbal product sales[2]

Notes

  1. Shekelle et al, Ephedra, JAMA March 26, 2003;289:1537-1545
  2. Bent et al, Ann Intern Med March 18, 2003;138:468-471