Ecstasy (MDMA)
This is often called the original designer drug because of its synonymous relationship with rave culture in the early 90s. Clubbers took ecstasy to stay awake and dance for hours. The effects take about half an hour to kick in and tend to last between 3 to 6 hours, followed by a gradual comedown[1].
Resources
Carey J., Recreational drug wars: alcohol versus ecstasy, Ecstasy.Com